National Niemann-Pick Disease Foundation

In 1992, six families with children affected by Niemann-Pick disease met at the National Institutes of Health and decided they would not accept that nothing could be done. Today the National Niemann-Pick Disease Foundation (NNPDF) is the largest Niemann-Pick disease family support organization in the world, connecting patients, caregivers, clinicians and researchers through education, community and research.

Their website had not kept pace with that mission. Built on, patched and added to for more than twelve years, it had become hard for families to navigate and harder still for the NNPDF team to keep current. It was time for a fresh start.

Twelve Years of

Layers

Upon Layers

NNPDF’s website had never truly been redone. Every new program, campaign and event was added on top of what came before, until the structure itself got in the way.

For many site visitors, the search for information happens at the hardest moment of their lives: right after a diagnosis. They are looking for answers, support and someone who understands.

The main menu kept growing until it was unwieldy and overwhelming at first glance. Once visitors clicked in, they found long pages of unbroken text and information that was difficult to take in. Worse, the site was hard to navigate, and when people couldn’t find the answers they came for, it was hard to find their way back.

years of additions without a true redesign

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links crowded into the main menu

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pages built up layer by layer

Information Hard to Find,

Harder

to Keep Current

Behind the scenes, the team was working around aging plugins, outdated systems and page layouts that broke when they were touched. Posting a new event or updating a clinic listing meant fighting twelve years of technical debt.

Leadership needed a site that reflected who NNPDF is today, and one they could confidently keep up to date themselves.

Support for Families,

Trusted

by Clinicians & Researchers

Niemann-Pick disease is serious, and the site needed to say so honestly. But many of the people who arrive are parents holding a brand-new diagnosis. The new look had to feel like a hand on the shoulder: warm, hopeful and human.

So real families lead the way. Photos from NNPDF conferences and family events fill the site instead of stock imagery. Soft blues, warm cream and the NNPDF butterfly gold set a calm tone, and plain-language headlines speak directly to the reader: “You don’t have to navigate them alone.” Family Stories and Community Voices give every family a place to be heard.

Credibility for the

Clinical

Community

At the same time, physicians, researchers and industry partners needed to see the clarity and credibility they expect from a scientific resource.

A dedicated section brings clinical trials, funded research, publications and the patient registry together. Disease pages were reviewed line by line with NNPDF leadership for clinical accuracy, with care-team detail on diagnosis and testing alongside a family-friendly overview, and illustrated diagrams that explain what happens inside the cell.

Helping Every Visitor

Find Their Way

We started with people, not pages. NNPDF serves two very different audiences: families who need clear information and real support, and the scientific community looking for research, data and funding opportunities. Every decision had to work for both.

Working from a detailed content plan with Executive Director Heather Teal and the NNPDF team, we rebuilt the site map around who visitors are and what they came to do. Patients & Families covers diagnosis and treatment, support, programs, caregivers and advocacy. The Science gathers research, learning and ways to participate. Get Involved, News & Events and About Us round it out. Grouped mega menus, a type-ahead search and clear section headings put every page a click or two away.

A Site That Meets You Where

You Are Today

New visitors are met with three simple paths: I just got a diagnosis, I’m learning the basics and I need support now. Each leads straight to the guidance that fits that moment.

Accessibility was built in from the start: high-contrast text, underlined links that are easy to spot, larger readable type, a logical heading structure, faster page loads and layouts tested on every screen from wide desktops to small phones.

A Website Built for the Team

That Runs It

The new site runs on a modern WordPress platform with a shared library of page designs, so staff can add events, stories and updates without breaking a layout. Newsletters and family stories list themselves as they are published.

The site is built with professional development and layout tools that offer incredible flexibility, yet are easy for the NNPDF team to pick up and use. Site-wide styles and a design guide help them keep the new look and feel consistent as they add content, now and in the years to come.

A Fresh Face for a

Lasting

Mission

The new nnpdf.org launched in October 2026, alongside NNPDF’s new Family Toolkit. Families can find answers faster, clinicians and partners see an organization that looks as credible as its work, and the NNPDF team finally has a site they can own.

The response from the community has been overwhelmingly positive, and the refreshed look has raised the profile of the foundation with everyone it serves.

Supporting Families &

Advancing Care

A Partner Who Understands

Our Mission

“Our old website had grown up over twelve years, one patch at a time. Rampant Imaginations helped us step back and rebuild it around the families we serve. It finally looks like the organization we are: warm and welcoming for families, and credible for the clinicians and researchers who rely on us. The feedback from our community has been wonderful.”

Heather Teal
Executive Director, National Niemann-Pick Disease Foundation

No Matter Who Your Audience Is,

We’ll Help

You Reach Them

Whether you speak to one audience or many, the right message has to reach each of them in a way that feels personal. Customers and partners, families and professionals, donors and volunteers: we’ll help you find the words, the look and the structure that connect with every one.

Tell us who you need to reach, and we’ll help you get there.